Full Description
Identifies a transmembrane protein specific to urothelial cells, serving as a marker of transitional cell epithelium and tumors. In normal urothelium, UPIII is expressed on the luminal surface of superficial cells. It is highly specific but only moderately sensitive for detecting urothelial carcinomas and may reflect malignant potential.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1