Synonyms
Thymidylate Synthase
Full Description
Identifies Thymidylate Synthase (TS), a protein targeted by fluoropyrimidine chemotherapies. TS expression can help predict response to 5-FU–based treatments in breast, colorectal, gastric, head, and neck cancers.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
Global: 48 Hrs, Tech-Only (stain only): 24 Hrs
CPT Codes
88342x1 or 88341x1 (qualitative IHC) or 88360x1 (quantitative/semi-quantitative – manual)