IHC

TDT

Identifies a specialized DNA polymerase present in immature pre-B and pre-T lymphoid cells, as well as most precursor B- and T-lymphoblastic leukemias/lymphomas. Useful for distinguishing lymphoblastic lymphoma from Burkitt lymphoma, with occasional aberrant expression in some acute myeloid leukemias.

Synonyms

Terminal Deoxynucleotidyl Transferase

Full Description

Identifies a specialized DNA polymerase present in immature pre-B and pre-T lymphoid cells, as well as most precursor B- and T-lymphoblastic leukemias/lymphomas. Useful for distinguishing lymphoblastic lymphoma from Burkitt lymphoma, with occasional aberrant expression in some acute myeloid leukemias.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1