Synonyms
T-cell Leukemia/Lymphoma Protein 1
Full Description
Identifies a protein expressed in the cytoplasm and nucleus of immature T cells, T-cell prolymphocytic leukemia, and various B-cell neoplasms, including CLL/SLL and blastic plasmacytoid dendritic cell tumors. It is used to help distinguish B-cell lymphomas from T-cell lymphomas, CD30+ anaplastic large cell lymphoma, multiple myeloma, and marginal zone B-cell lymphoma.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1