Synonyms
Signal Transducers and Activators of Transcription 6
Full Description
Identifies STAT6, a transcription factor normally in the cytoplasm that translocates to the nucleus upon activation. Nuclear STAT6 immunoreactivity serves as a surrogate marker for NAB2-STAT6 gene fusions, which are characteristic of solitary fibrous tumors/hemangiopericytomas, aiding in their identification.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1