IHC

SS18-SSX

Identifies the SS18-SSX fusion protein resulting from the t(X;18)(p11.2;q11.2) translocation, which is characteristic of synovial sarcoma. Detection by IHC or molecular methods helps confirm the diagnosis of synovial sarcoma and distinguish it from other soft tissue tumors.

Full Description

Identifies the SS18-SSX fusion protein resulting from the t(X;18)(p11.2;q11.2) translocation, which is characteristic of synovial sarcoma. Detection by IHC or molecular methods helps confirm the diagnosis of synovial sarcoma and distinguish it from other soft tissue tumors.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1