Molecular

Solid Tumor Fusion/Expression Profile

RNA-based next-generation sequencing to detect clinically relevant information on translocations and expression of more than 60 cancer-specific genes, including ALK, ROS1, RET,NTRK1, NTRK2, NTRK3, BRAF, CIC, EWSR1, PD-L1, and others. This also covers screening for sarcoma translocations and aids in sarcoma diagnosis and classification. Other genes of clinical relevance are reported including MYC,PD-L1, and more.

Full Description

RNA-based next-generation sequencing to detect clinically relevant information on translocations and expression of more than 60 cancer-specific genes, including ALK, ROS1, RET,NTRK1, NTRK2, NTRK3, BRAF, CIC, EWSR1, PD-L1, and others. This also covers screening for sarcoma translocations and aids in sarcoma diagnosis and classification. Other genes of clinical relevance are reported including MYC,PD-L1, and more.

Methodology

Molecular

Specimen Requirements

Formalin-fixed, paraffin-embedded(FFPE): 1 H&E slide, plus 6-10, at 5 or more microns fix with 10% NBF fixative. Please circle tumor for microdissection. Alternatively, the FFPE block can be sent for tumor circling and cutting at our laboratory.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

7-10 days

CPT Codes

81455