IHC

SATB2

Acts as a marker for colorectal and appendiceal carcinomas, tumors with osteoblastic differentiation such as osteosarcoma, and renal/urothelial tumors. It stains colonic and osteogenic cells and their neoplasms, making it useful in the evaluation of carcinoma of unknown primary.

Synonyms

Special AT-rich Sequence-Binding Protein 2

Full Description

Acts as a marker for colorectal and appendiceal carcinomas, tumors with osteoblastic differentiation such as osteosarcoma, and renal/urothelial tumors. It stains colonic and osteogenic cells and their neoplasms, making it useful in the evaluation of carcinoma of unknown primary.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1