Full Description
Identifies a zinc-finger transcription factor essential for maintaining embryonic cell pluripotency through modulation of OCT4. It is a highly sensitive and specific marker for germ cell tumors, including seminoma, embryonal carcinoma, yolk sac tumor, and choriocarcinoma, with occasional positivity in a subset of gastric carcinomas.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1