IHC

PIT-1

Identifies a nuclear transcription factor involved in pituitary development and hormone regulation. PIT-1 is expressed in somatotroph, lactotroph, and thyrotroph cells and is useful for classifying pituitary adenomas based on lineage differentiation.

Full Description

Identifies a nuclear transcription factor involved in pituitary development and hormone regulation. PIT-1 is expressed in somatotroph, lactotroph, and thyrotroph cells and is useful for classifying pituitary adenomas based on lineage differentiation.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1