IHC

PD-L1 (EIL3N)

Identifies programmed death-ligand 1 (PD-L1), a cell surface protein involved in immune evasion by tumor cells. PD-L1 expression helps assess eligibility for immune checkpoint inhibitor therapies and is seen in a variety of cancers, including lung, breast, bladder, and melanoma. The E1L3N clone is widely used for evaluating PD-L1 expression in tumor and immune cells within the tumor microenvironment.

Full Description

Identifies programmed death-ligand 1 (PD-L1), a cell surface protein involved in immune evasion by tumor cells. PD-L1 expression helps assess eligibility for immune checkpoint inhibitor therapies and is seen in a variety of cancers, including lung, breast, bladder, and melanoma. The E1L3N clone is widely used for evaluating PD-L1 expression in tumor and immune cells within the tumor microenvironment.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1