IHC

Olig 2

Identifies a transcription factor involved in oligodendroglial specification and development. It is expressed in most glial tumors, including oligodendrogliomas and astrocytomas, but is negative in non-glial tumors such as ependymomas, medulloblastomas, CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumors, and hemangioblastomas.

Full Description

Identifies a transcription factor involved in oligodendroglial specification and development. It is expressed in most glial tumors, including oligodendrogliomas and astrocytomas, but is negative in non-glial tumors such as ependymomas, medulloblastomas, CNS lymphomas, meningiomas, schwannomas, atypical teratoid/rhabdoid tumors, and hemangioblastomas.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1