Synonyms
N-Cadherin
Full Description
Identifies a calcium-dependent cell adhesion molecule expressed in neural tissues, myocardium, skeletal muscle, and certain tumors such as neuroendocrine, synovial sarcomas, and melanomas. It is useful in distinguishing prostate adenocarcinoma (typically negative) from prostatic basal cells and other tumor types showing mesenchymal or neural differentiation.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1