Molecular

MPL Mutation Analysis

Bi-directional sequencing analysis on MPL exon 10 to detect all possible mutations including W515(present in patients with primary myelofibrosis and essential thrombocythemia) andS505, present in patients with hereditary thrombocythemia. It also helps to differentiate reactive conditions from Myeloproliferative Neoplasms.

Full Description

Bi-directional sequencing analysis on MPL exon 10 to detect all possible mutations including W515(present in patients with primary myelofibrosis and essential thrombocythemia) andS505, present in patients with hereditary thrombocythemia. It also helps to differentiate reactive conditions from Myeloproliferative Neoplasms.

Methodology

Molecular

Specimen Requirements

Whole blood (3-5 mL), Bone marrow(1-2 mL), in Lavender-top (EDTA) tube.

Storage and Transportation

Use cold pack for transport but not in direct contact with specimen. Ship same day as drawn whenever possible.

Turnaround Time

10 days

CPT Codes

81339