IHC

MITF

Identifies a nuclear protein regulating melanocyte development and survival, expressed in most melanomas and normal or benign melanocytic lesions. MITF expression is restricted to the melanocyte lineage.

Synonyms

Microphthalmia Associated Transcription Factor

Full Description

Identifies a nuclear protein regulating melanocyte development and survival, expressed in most melanomas and normal or benign melanocytic lesions. MITF expression is restricted to the melanocyte lineage.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1