IHC

Mesothelin

Identifies a cell surface glycoprotein expressed in mesothelial cells and malignant mesothelioma, as well as in various carcinomas including ovarian, breast, pancreatic, and squamous tumors. Less specific for mesothelioma compared to WT-1, calretinin, and podoplanin.

Full Description

Identifies a cell surface glycoprotein expressed in mesothelial cells and malignant mesothelioma, as well as in various carcinomas including ovarian, breast, pancreatic, and squamous tumors. Less specific for mesothelioma compared to WT-1, calretinin, and podoplanin.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1