IHC

LMO2

Identifies a cysteine-rich protein involved in hematopoietic development, expressed in germinal center B-cells, endothelial cells, and hematopoietic precursors. It is useful in distinguishing germinal center B-cell–type diffuse large B-cell lymphomas (DLBCLs) from non-germinal center types and is rarely expressed in mature T, NK, or plasma cell neoplasms.

Synonyms

LIM-Domain Only 2

Full Description

Identifies a cysteine-rich protein involved in hematopoietic development, expressed in germinal center B-cells, endothelial cells, and hematopoietic precursors. It is useful in distinguishing germinal center B-cell–type diffuse large B-cell lymphomas (DLBCLs) from non-germinal center types and is rarely expressed in mature T, NK, or plasma cell neoplasms.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1