Full Description
Detects lambda light chain immunoglobulin mRNA in plasma cells, plasmacytoid cells, and immunoblasts. Useful for assessing light chain restriction to distinguish neoplastic from reactive lymphoid proliferations and for evaluating multiple myeloma, plasmacytoma, and related B-cell disorders.
Methodology
ISH
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
48 Hrs
CPT Codes
88365x1 or 88364x1