Full Description
Identifies the lambda light chain of immunoglobulins, useful in diagnosing leukemias, plasmacytomas, and certain non-Hodgkin lymphomas. A decreased kappa-to-lambda ratio indicates lambda light chain restriction, serving as a marker of B-cell clonality and malignancy.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1