IHC

Keratin AE1/AE3

A blend of two monoclonal antibodies targeting acidic and basic cytokeratins, expressed in most epithelial tumors. Useful for confirming carcinoma, distinguishing epithelial from non-epithelial tumors, and identifying carcinomas in undifferentiated malignancies.

Synonyms

Pancytokeratin

Full Description

A blend of two monoclonal antibodies targeting acidic and basic cytokeratins, expressed in most epithelial tumors. Useful for confirming carcinoma, distinguishing epithelial from non-epithelial tumors, and identifying carcinomas in undifferentiated malignancies.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1