Full Description
Detects cytokeratins 5 and 14, markers of basal and myoepithelial cells in stratified and complex epithelia. This cocktail is useful in identifying squamous differentiation, distinguishing basal-like breast carcinomas, and differentiating benign from malignant glandular lesions based on the presence or absence of basal/myoepithelial layers.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1