Synonyms
Insulinoma-associated protein 1
Full Description
Identifies a transcription factor that is a sensitive and specific marker for neuroendocrine tumors. As a nuclear stain, it is as good as or better than synaptophysin and is superior to chromogranin. It is rarely expressed on adenocarcinoma or squamous cell carcinomas without neuroendocrine differentiation.
Methodology
IHC
Specimen Requirements
A formalin-fixed, paraffin-embedded (FFPE) tissue block is preferred specimen typeorOne (1) unbaked, unstained slide for H&E staining (required) and two to three (2-3) positively charged unstained slides (all cut at 4-5 microns) for each test/antibody orderedBlock and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
Tech-Only (stain only): 24 hrs
CPT Codes
88342 x 1 or 88341 x 1