Full Description
DNA & RNA next generation sequencing (NGS) assay for a comprehensive evaluation of all hematologic neoplasms. The test covers 302 DNA genes and more than 1600 RNA genes. It is especially recommended for:Acute Myeloid Leukemia (AML)Clonal Hematopoiesis of Indeterminate Potential (CHIP)VEXAS Syndrome Acute Lymphoblastic Leukemia(ALL)Diffuse Large B-cell Lymphoma (DLBCL) and Other Types of Lymphoma or Plasma Cell NeoplasmsIgHV Mutation StatusT-cell and B-cell Clonality DetectionEpstein-Barr Virus (EBV)Torque Teno Virus (TTV)Other Features of Hematology Profile Plus:HLA class I genotypingEnrichment for CD138-positive plasma cells is performed on bone marrow specimens with the clinical indication of multiple myelomaA preliminary report will be issued for any patient positive for FLT3-ITD by fragment analysis or with a clinical indication of acute leukemia
Methodology
Molecular
Specimen Requirements
Bone marrow: 2 mL; EDTA tube is preferred. Peripheral blood: 5-10 mL; EDTA tube is preferred. Fresh Tissue FFPE: 1 H&E slide and 8-10 unstained slides, 5-7microns of BM clot or tissue fixed with 10% NBF fixative. Alternatively, the FFPE block of the BM clot can be sent for sectioning in our Lab.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
8-11 days
CPT Codes
81455