Full Description
A heparan sulfate proteoglycan highly expressed in hepatocellular carcinoma and yolk sac tumors. Glypican-3 is more sensitive and specific than AFP and HepPar1 for HCC, and it helps distinguish malignant liver lesions (positive) from benign liver conditions (negative).
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1