IHC

GCDFP-15

Detects a 15 kDa protein expressed in apocrine epithelia, lacrimal, ceruminous, and Moll’s glands, as well as serous cells of salivary, tracheal, and bronchial glands. GCDFP-15 is used to identify breast carcinoma, sweat gland carcinoma, and a subset of salivary gland carcinomas. It may also be expressed in about 10% of primary lung adenocarcinomas.

Synonyms

BRST-2; Gross Cystic Disease Fluid Protein 15

Full Description

Detects a 15 kDa protein expressed in apocrine epithelia, lacrimal, ceruminous, and Moll’s glands, as well as serous cells of salivary, tracheal, and bronchial glands. GCDFP-15 is used to identify breast carcinoma, sweat gland carcinoma, and a subset of salivary gland carcinomas. It may also be expressed in about 10% of primary lung adenocarcinomas.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1