Synonyms
GAL3
Full Description
A lectin-family protein that localizes to the cytoplasm and nucleus. Galectin-3 is up regulated in thyroid carcinomas, particularly papillary thyroid carcinoma, and helps distinguish malignant thyroid tumors from benign adenomas. It is commonly used as part of a panel to differentiate benign from malignant thyroid neoplasms.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1