IHC

FSH

A pituitary hormone produced by gonadotrophs that regulates reproductive function. In females, FSH promotes ovarian follicle maturation and estrogen production; in males, it stimulates spermatogenesis and testosterone secretion. Immunohistochemical detection is useful for identifying FSH in pituitary adenomas and differentiating primary from secondary ovarian failure.

Synonyms

Follicle Stimulating Hormone

Full Description

A pituitary hormone produced by gonadotrophs that regulates reproductive function. In females, FSH promotes ovarian follicle maturation and estrogen production; in males, it stimulates spermatogenesis and testosterone secretion. Immunohistochemical detection is useful for identifying FSH in pituitary adenomas and differentiating primary from secondary ovarian failure.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1