Full Description
A nuclear transcription factor expressed primarily in ovarian granulosa cells. FOXL2 is a key regulator of ovarian development and function and is useful in identifying sex cord-stromal tumors of the ovary, particularly adult granulosa cell tumors. It helps differentiate these tumors from other ovarian neoplasms.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not indirect contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1