Synonyms
Von Willebrand factor, vWF, VMF8
Full Description
Identifies von Willebrand factor, a protein synthesized by endothelial cells and stored in Weibel-Palade bodies. It is also present in platelets and megakaryocytes. Immunohistochemical detection is useful for identifying endothelial cells, diagnosing vascular neoplasms, and detecting vascular invasion by tumors.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE)tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1