IHC

CD8

A cell surface protein highly expressed on cytotoxic/suppressor T cells, with lower expression on γδ T cells and NK cells. Also present on most thymocytes, some null cells, and bone marrow cells. Expression may be decreased in certain T-cell and NK-cell neoplasms, making it useful in evaluating T-cell lymphomas.

Full Description

A cell surface protein highly expressed on cytotoxic/suppressor T cells, with lower expression on γδ T cells and NK cells. Also present on most thymocytes, some null cells, and bone marrow cells. Expression may be decreased in certain T-cell and NK-cell neoplasms, making it useful in evaluating T-cell lymphomas.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1