IHC

CD43

A cell surface glycoprotein expressed on all thymocytes, T cells, myeloid lineage cells, and most leukocytes except resting B cells. Useful in identifying T-cell lymphomas and a subset of B-cell lymphomas. Co-expression with CD20 occurs in some low-grade lymphomas, and expression is often correlated with CD5; follicular lymphoma is rarely positive.

Full Description

A cell surface glycoprotein expressed on all thymocytes, T cells, myeloid lineage cells, and most leukocytes except resting B cells. Useful in identifying T-cell lymphomas and a subset of B-cell lymphomas. Co-expression with CD20 occurs in some low-grade lymphomas, and expression is often correlated with CD5; follicular lymphoma is rarely positive.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1