IHC

CD25

A cell surface protein that serves as the interleukin-2 receptor. Strongly expressed in neoplastic T cells of adult T-cell leukemia/lymphoma, anaplastic large cell lymphoma, hairy cell leukemia, classical Hodgkin lymphoma, and some peripheral T-cell lymphomas. Aberrant expression on mast cells aids in diagnosing systemic mastocytosis.

Full Description

A cell surface protein that serves as the interleukin-2 receptor. Strongly expressed in neoplastic T cells of adult T-cell leukemia/lymphoma, anaplastic large cell lymphoma, hairy cell leukemia, classical Hodgkin lymphoma, and some peripheral T-cell lymphomas. Aberrant expression on mast cells aids in diagnosing systemic mastocytosis.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1