IHC

CD23

A cell surface protein expressed on a subset of peripheral blood cells, B lymphocytes, EBV-transformed B-lymphoblastoid lines, and many follicular dendritic cells. Useful for distinguishing CLL/SLL from other B-cell neoplasms and often strongly coexpressed with CD5 on these B cells.

Full Description

A cell surface protein expressed on a subset of peripheral blood cells, B lymphocytes, EBV-transformed B-lymphoblastoid lines, and many follicular dendritic cells. Useful for distinguishing CLL/SLL from other B-cell neoplasms and often strongly coexpressed with CD5 on these B cells.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1