IHC

CD22

A B-cell–specific surface antigen expressed on mature normal and neoplastic B cells, including mantle cell lymphoma, CLL/SLL, hairy cell leukemia, and follicular, mantle, and marginal zone B-cells. Weakly expressed in germinal center B cells and absent from other hematopoietic lineages.

Full Description

A B-cell–specific surface antigen expressed on mature normal and neoplastic B cells, including mantle cell lymphoma, CLL/SLL, hairy cell leukemia, and follicular, mantle, and marginal zone B-cells. Weakly expressed in germinal center B cells and absent from other hematopoietic lineages.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 Hrs

CPT Codes

88342x1 or 88341x1