Full Description
A cell surface-associated protein expressed strongly on mature B-cells, follicular dendritic cells of lymphoid tissues and derived tumors, and weakly on immature thymocytes and T-lymphocytes. A variety of lymphomas display disruption of CD21-positive follicular dendritic cell networks and precursor B-cell lymphomas, Burkitt lymphomas, plasmacytomas, and hairy cell leukemias lack CD21 expression.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342x1 or 88341x1