Synonyms
X-Hapten
Full Description
A cytoplasmic and cell-surface protein involved in phagocytosis, chemotaxis, and bactericidal activity. Strongly expressed in granulocytes, with weaker expression in monocytes/histiocytes, Reed-Sternberg cells, some epithelial cells, and occasionally large B- and T-cell lymphomas. Useful in identifying Hodgkin lymphoma.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain), baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 Hrs
CPT Codes
88342 x 1 or 88341 x 1