Synonyms
CALD, h-Caldesmon
Full Description
Regulatory protein expressed in smooth muscle and related tissues. Useful for identifying smooth muscle, myofibroblastic, and myoepithelial tumors, including leiomyosarcoma, and for differentiating epithelioid mesothelioma from serous papillary ovarian carcinoma. Typically negative in endometrial stromal tumors.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
24 hrs
CPT Codes
88342x1 or 88341x1