IHC

CA-125

A tumor marker for epithelial ovarian carcinomas, including serous, endometrioid, clear cell, and undifferentiated types. Also positive in some fallopian tube, endometrial, endocervical, and mesothelial neoplasms, but negative in mucinous ovarian tumors, colon cancer, and most normal tissues.

Synonyms

Cancer Antigen 125

Full Description

A tumor marker for epithelial ovarian carcinomas, including serous, endometrioid, clear cell, and undifferentiated types. Also positive in some fallopian tube, endometrial, endocervical, and mesothelial neoplasms, but negative in mucinous ovarian tumors, colon cancer, and most normal tissues.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2 charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 hrs

CPT Codes

88342x1 or 88341x1