IHC

Annexin-A1 (ANXA1)

Detects a phagocytosis-associated gene product that is markedly upregulated in hairy cell leukemia, and shows reactivity in myeloid cells, macrophages, and certain benign T-cell subsets. Identifies a gene related to phagocytosis, found to be highly upregulated in hairy cell leukemia, and stains myeloid cells, macrophages, and subsets of benign T-cells.

Synonyms

lipocortin-1, calpactin II

Full Description

Detects a phagocytosis-associated gene product that is markedly upregulated in hairy cell leukemia, and shows reactivity in myeloid cells, macrophages, and certain benign T-cell subsets. Identifies a gene related to phagocytosis, found to be highly upregulated in hairy cell leukemia, and stains myeloid cells, macrophages, and subsets of benign T-cells.

Methodology

IHC

Specimen Requirements

Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumorblock preferred. Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.

Storage and Transportation

Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.

Turnaround Time

24 hrs

CPT Codes

88342x1 or 88341x1