Full Description
Marks cells involved in regulating prostate epithelial growth and is expressed in a subset of carcinomas, including those of the prostate, breast, and salivary gland. In untreated prostate cancer, AR positivity is associated with potential responsiveness to hormonal therapy, whereas in hormone-refractory disease, AR expression is linked to poorer prognosis.
Methodology
IHC
Specimen Requirements
Tissue Block: Formalin-fixed, paraffin-embedded (FFPE) tumor block preferred. Unstained Slides: Recommended 2charged slides per stain requested (minimum of 1 slide per stain),baked or unbaked. Fixation: Tissue must be fixed in 10% neutral buffered formalin for 6–72 hours.
Storage and Transportation
Use cold pack for transport. Make sure cold pack is not in direct contact with specimen.
Turnaround Time
Global: 48 hrs, Image Analysis (tech-only): 36 hrs, Tech-Only (stain only): 24 hrs
CPT Codes
88342x1 or 88341x1; or 88360x1; or 88361x1